Meinke, C., Lueken, U., Walter, H., & Hilbert, K. (2024). Predicting treatment outcome based on resting-state functional connectivity in internalizing mental disorders: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, 160, 105640. https://doi.org/10.1016/j.neubiorev.2024.105640
Publications
Publications from the research group
Original Work
Meinke, C., Hornstein, S., Schmidt, J., Arolt, V., Dannlowski, U., Deckert, J., Domschke, K., Fehm, L., Fydrich, T., Gerlach, A. L., Hamm, A. O., Heinig, I., Hoyer, J., Kircher, T., Koelkebeck, K., Lang, T., Margraf, J., Neudeck, P., Pauli, P., … Hilbert, K. (2024). Advancing the personalized advantage index (PAI): A systematic review and application in two large multi-site samples in anxiety disorders. Psychological Medicine, 54(16), 4843–4855. https://doi.org/10.1017/S0033291724003118
Jüres, F., Kaufmann, C., Riesel, A., Grützmann, R., Heinzel, S., Elsner, B., Bey, K., Wagner, M., Kathmann, N., & Klawohn, J. (2024). Heart rate and heart rate variability in obsessive-compulsive disorder: Evidence from patients and unaffected first-degree relatives. Biological Psychology, 189, 108786. https://doi.org/10.1016/j.biopsycho.2024.108786
Torbecke, J., Langhammer, T., Mewes, L., Lueken, U., & Fendel, J. C. (2024). Augmentation of cognitive-behavioural therapy for obsessive-compulsive and anxiety disorders: A protocol for a systematic review and meta-analysis. BMJ Open, 14(10), e090431. https://doi.org/10.1136/bmjopen-2024-090431
Hammelrath, L., Hilbert, K., Heinrich, M., Zagorscak, P., & Knaevelsrud, C. (2024). Select or adjust? How information from early treatment stages boosts the prediction of non-response in internet-based depression treatment. Psychological Medicine, 54(8), 1641–1650. https://doi.org/10.1017/S0033291723003537
Hilbert, K., Weller, P., Ritter, K., Haynes, J.-D., Walter, H., & Lueken, U. (2024). Design studies for clinical prediction. Science, 385(6709), 613–613. https://doi.org/10.1126/science.adp1063
Hilbert, K., Böhnlein, J., Meinke, C., Chavanne, A. V., Langhammer, T., Stumpe, L., Winter, N., Leenings, R., Adolph, D., Arolt, V., Bischoff, S., Cwik, J. C., Deckert, J., Domschke, K., Fydrich, T., Gathmann, B., Hamm, A. O., Heinig, I., Herrmann, M. J., … Lueken, U. (2024). Lack of evidence for predictive utility from resting state fMRI data for individual exposure-based cognitive behavioral therapy outcomes: A machine learning study in two large multi-site samples in anxiety disorders. NeuroImage, 295, 120639. https://doi.org/10.1016/j.neuroimage.2024.120639
Congress and press contributions
Sprengel, R., & Klawohn, J. (2024, October 9). Studying emotion regulation and inhibition in emotionally unstable personality disorder with psychophysiology—STEPS study protocol [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Wewers, R., Jüres, F., Kathmann, N., & Klawohn, J. (2024, June 11). Electrophysiological measures of emotional reactivity and emotion regulation in patients & healthy controls [Poster presentation]. 3. Deutscher Psychotherapie Kongress, Berlin, Germany.
Wewers, R., Jüres, F., Kathmann, N., & Klawohn, J. (2024, June 29). Electrophysiological measures of emotional reactivity and emotion regulation in patients & healthy controls [Poster presentation]. The 49th Annual Meeting of Psychologie und Gehirn, Hamburg, Germany.
Sprengel, R., Jüres, F., Hajcak, G., Kathmann, N., & Klawohn, J. (2024, October 23). ELECTROPHYSIOLOGICAL MEASURES OF EMOTIONAL REACTIVITY AND EMOTION REGULATION IN HEALTHY INDIVIDUALS AND PATIENTS WITH INTERNALIZING DISORDERS [Poster presentation]. Annual Meeting of the Society for Psychophysiological Research, Prague, Czech Republic.
Jüres, F., Wewers, R., Hajcak, G., Kathmann, N., & Klawohn, J. (2024, June 11-15). Understanding Feedback Processing in Reward Tasks: A Comparison of Electrophysiological Correlates (RewP and P300) Across Two Paradigms [Poster presentation]. 3. Deutscher Psychotherapie Kongress, Berlin, Germany.
Jüres, F., Wewers, R., Hajcak, G., Kathmann, N., & Klawohn, J. (2024, May 28-June 1). Neural correlates of feedback processing in internalizing disorders: A comparison of guessing and learning scenarios [Poster presentation]. The 49th Annual Meeting of Psychologie und Gehirn, Hamburg, Germany.
Jüres, F., Wewers, R., Hajcak, G., Kathmann, N., & Klawohn, J. (2024, October 9). Neural Correlates of Feedback Processing in Internalizing Disorders: A Comparison of Guessing and Learning Scenarios [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Wellan, S., Daniels, A., Schnell, Kruschwitz, J. D., & Walter, H. (2024, July 10-13). Neural correlates of meaning in life in resting-state fMRI [Poster presentation]. ECPP2024, Innsbruck, Austria.
Wellan, S., Daniels, A., & Walter, H. (2024, July 10-13). Associations of hedonic and eudaimonic motives for activities with mental health and life satisfaction. A longitudinal survey study [Poster presentation]. ECPP2024, Innsbruck, Austria.
Wellan, S., Daniels, A., & Walter, H. (2024, September 25). Facets of Anhedonia. Differentiating anticipatory pleasure, consummatory pleasure and hedonic domains as prospective resilience factors [Poster presentation]. DZPG Annual Conference, Berlin, Germany.
Wellan, S., Heinzel, S., & Walter, H. (2024, October 9). Predicting mental health symptoms with NBS-Predict [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Wyka, S., Fehm, L., Jacobi, F., Kathmann, N., Lueken, U., Renneberg, B., Langhammer, T., Fliedner, L., Künstler, A., Sauder, T., Unterfeld, C., & Stenzel, N. (2024, September 16-19). Illness Perceptions (IP) – ein unterschätzter Faktor bei internalisierenden Störungen [Poster presentation]. 53rd Congress of the German Psychological, Vienna, Austria.
Wyka, S., Fehm, L., Jacobi, F., Kathmann, N., Lueken, U., Renneberg, B., Langhammer, T., Fliedner, L., Künstler, A., Sauder, T., Unterfeld, C., & Stenzel, N. (2024, June 11-15). Illness Perception Questionnaire—Mental Health (IPQ-MH): Ein neues ökonomisches Selbstbeurteilungsinstrument mit guten psychometrischen Eigenschaften [Poster presentation]. 3. Deutscher Psychotherapie Kongress, Berlin, Germany.
Wyka, S., Fehm, L., Jacobi, F., Kathmann, N., Lueken, U., Renneberg, B., Langhammer, T., Fliedner, L., Künstler, A., Sauder, T., Unterfeld, C., & Stenzel, N. (2024, October 9). Illness Perceptions – Have we been underestimating the relevance of the factor in internalising disorders? – An evaluation of the psychometric properties of the German Illness Perception Questionnaire Mental Health (IPQ-MH) [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Langhammer, T., Unterfeld, C., Blankenburg, F., Erk, S., Fehm, L., Haynes, J.-D., Heinzel, S., Hilbert, K., Jacobi, F., Kathmann, N., Knaevelsrud, C., Renneberg, B., Ritter, K., Stenzel, N., Walter, H., & Lueken, U. (2024, June 26). Towards precision psychotherapy for non-respondent patients: Design and methods of a naturalistic observational CBT-trial for single-case prediction with machine learning [Poster presentation]. Annual SPR Meeting, Ottawa, Canada.
Langhammer, T., Blankenburg, F., Erk, S., Fehm, L., Haynes, J.-D., Heinzel, S., Hilbert, K., Jacobi, F., Kathmann, N., Knaevelsrud, C., Renneberg, B., Ritter, K., Stenzel, N., Walter, H., & Lueken, U. (2024, October 9). Towards Precision Psychotherapy for Non‐Respondent Patients: Recruitment Status and Descriptive Analysis of a Naturalistic Observational CBT Trial for Single‐Case Prediction with Machine Learning [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Tochadse, M., Gijsen, S., Rane, R. P., Lueken, U., Klawohn, J., Kathmann, N., & Ritter, K. (2024, October 9). BOLD variability and normative modelling feature construction for prediction in mental health [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Weller, P., Hilbert, K., Consortium, T. K., & Lueken, U. (2024, October 9). Network Characteristics of Remitters and Non-Remitters to Psychotherapy in a Heterogeneous sample of Patients with Internalising Disorders [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Weller, P., Hilbert, K., Consortium, T. K., & Lueken, U. (2024, October 9). Clinical Prediction Models show Poor Generalization across a Naturalistic Sample of Outpatient Clinics [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Henze, G.-I., Giglberger, M., Bärtl, C., Konzok, J., Neidhart, M., Krause, T., Serin, E., Waller, L., Peter, H. L., Speicher, N., Kreuzpointner, L., Streit, F., Veer, I., Erk, S., Kirsch, P., Kudielka, B. M., Nichols, T. E., Wüst, S., & Walter, H. (2024, October 9). The Ups and Downs of Brain Stress: Testing the Triple Network Hypothesis in a Largescale Biopsychological Sample [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Hammelrath, L., Bimüller, G., Gas, B., Brose, A., & Knaevelsrud, C. (2024, October 9). Behind the spotlight: Using EMA and passive sensing to depict situational context in a clinical sample [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Gijsen, S., & Ritter, K. (2024, October 9). Self-supervised learning for encoding pathological between-subject information in EEG data [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Unterfeld, C. (2024, October 9). Towards Precision Psychotherapy for Non-Respondent Patients: Design and Methods of a Naturalistic Observational CBT Trial for Single-Case Prediction with Machine Learning [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Meinke, C. (2024, October 9). Advancing the Personalized Advantage Index (PAI): A Systematic Review and Application in Two Large Multi-Site Samples in Anxiety Disorders [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Meinke, C. (2024, October 9). Gradient mapping for the anterior cingulate cortex [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Gutmann, G. (2024, October 9). Decreased thalamic integration during distancing correlates with negative mood: A full-brain connectivity study in MDD using network-gppi [Poster presentation]. 5187 PREACT Symposium: Precision Psychotherapy Signatures, Predictions, & Clinical Utility, Berlin, Germany.
Hammelrath L., Heinrich M., Burggraf P., Schenk, H., Knaevelsrud C. (2023, June 5-7). Tell me how I feel! Development of an Algorithm to Predict Depression Symptoms Based on Wearable Data. [Poster presentation]. Society for Ambulatory Assessment, Amsterdam, Netherlands.
Meinke, C., Lueken, U., Walter, H., & Hilbert, K. (2023, May 10-13). Können Resting-State fMRT Konnektivität und maschinelles Lernen zur Prädiktion des individuellen Behandlungserfolgs genutzt werden? - Ein systematisches Review [Poster presentation]. 2. Deutscher Psychotherapie Kongress, Berlin, Germany.
Lueken, U. & FOR 5187 Konsortium (2023, May 9 -13). Personalisierte Psychotherapie für Patient:innen mit fehlendem Behandlungserfolg: Wie können wir unsere Prädiktionsmodelle verbessern? [Conference session]. 2. Deutscher Psychotherapie Kongress (DPK), Berlin, Germany.
Wewers, R., Kathmann, N., Jüres, F., Klawohn, J. (2023, May 9-13). Associations between emotion processing and self-reports of emotion regulation [Poster presentation]. 2. Deutscher Psychotherapie Kongress, Berlin, Germany.
Wewers, R., Kathmann, N., Jüres, F., Klawohn, J. (2023, June 8-10). Associations between emotion processing and self-reports of emotion regulation [Poster presentation]. 48th Conference „Psychologie und Gehirn“, Tübingen, Germany.
Jüres, F., Wewers, R., Hajcak, G., Kathmann, N., & Klawohn, J. (2023, September 27 - Octobter 01). Comparing electrophysiological correlates of feedback processing across reward tasks: RewP and P300 in two paradigms [Poster presentation]. Annual Meeting of the Society for Psychophysiological Research, New Orleans, USA.
Jüres, F., Wewers, R., Hajcak, G., Kathmann, N., & Klawohn, J. (2023, June 08-10). Neural feedback processing during a guessing and a learning paradigm: Comparison of the RewP and the P300 across tasks [Poster presentation]. 48th Conference „Psychologie und Gehirn“, Tübingen, Germany.
Jüres, F., Elsner, B., Kaufmann, C., Kathmann, N., & Klawohn, J. (2023, May 09-13). Heart rate variability as a potential predictor for treatment outcome in patients with obsessive-compulsive disorder [Poster presentation]. 2. Deutscher Psychotherapie Kongress, Berlin, Germany.
Wewers, R., Kathmann, N., Jüres, F., Klawohn, J. (2023, September 27-October 1). Associations between emotion processing and self-reports of emotion regulation [Poster presentation]. Annual Meeting of the Society for Psychophysiological Research, New Orleans, USA.
Wellan, S., Daniels, A., & Walter, H. (2023, July 20-23). Neural correlates of hedonic functioning during pleasant touch [Poster presentation]. IPPA 2023, Vancouver, Canada.
Lueken, U., Hilbert, K., Kathmann, N., Hahn, T., Straube, B., Kircher, T., Wittchen, H.-U., Dannlowski, U. (2022, September 10-15). Precision Psychotherapy: From signatures to predictions to clinical utility [Conference session]. 52nd Congress of the German Society of Psychology (DGPs), Hildesheim, Germany.
Further publications by members of the research group
Leehr, E. J., Seeger, F. R., Böhnlein, J., Gathmann, B., Straube, T., Roesmann, K., Junghöfer, M., Schwarzmeier, H., Siminski, N., Herrmann, M. J., Langhammer, T., Goltermann, J., Grotegerd, D., Meinert, S., Winter, N. R., Dannlowski, U., & Lueken, U. (2024). Association between resting-state connectivity patterns in the defensive system network and treatment response in spider phobia—A replication approach. Translational Psychiatry, 14(1), 137. https://doi.org/10.1038/s41398-024-02799-x
Hilbert, K., Boeken, O. J., Langhammer, T., Groenewold, N. A., Bas-Hoogendam, J. M., Aghajani, M., Zugman, A., Åhs, F., Arolt, V., Beesdo-Baum, K., Björkstrand, J., Blackford, J. U., Blanco-Hinojo, L., Böhnlein, J., Bülow, R., Cano, M., Cardoner, N., Caseras, X., Dannlowski, U., … Lueken, U. (2024). Cortical and Subcortical Brain Alterations in Specific Phobia and Its Animal and Blood-Injection-Injury Subtypes: A Mega-Analysis From the ENIGMA Anxiety Working Group. American Journal of Psychiatry, 181(8), 728–740. https://doi.org/10.1176/appi.ajp.20230032
Bruin, W. B., Zhutovsky, P., Van Wingen, G. A., Bas-Hoogendam, J. M., Groenewold, N. A., Hilbert, K., Winkler, A. M., Zugman, A., Agosta, F., Åhs, F., Andreescu, C., Antonacci, C., Asami, T., Assaf, M., Barber, J. P., Bauer, J., Bavdekar, S. Y., Beesdo-Baum, K., Benedetti, F., … Aghajani, M. (2024). Brain-based classification of youth with anxiety disorders: Transdiagnostic examinations within the ENIGMA-Anxiety database using machine learning. Nature Mental Health, 2(1), 104–118. https://doi.org/10.1038/s44220-023-00173-2
Schulz, M., Bzdok, D., Haufe, S., Haynes, J. & Ritter, K. (2024). Performance reserves in brain-imaging-based phenotype prediction. Cell Reports, 43(1), 113597. https://doi.org/10.1016/j.celrep.2023.113597
Langhammer, T., Hilbert, K., Adolph, D., Arolt, V., Bischoff, S., Böhnlein, J., Cwik, J. C., Dannlowski, U., Deckert, J., Domschke, K., Evens, R., Fydrich, T., Gathmann, B., Hamm, A. O., Heinig, I., Herrmann, M. J., Hollandt, M., Junghoefer, M., Kircher, T., … Lueken, U. (2024). Resting-state functional connectivity in anxiety disorders: A multicenter fMRI study. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02768-2
Chavanne, A. V., Meinke, C., Langhammer, T., Roesmann, K., Böhnlein, J., Gathmann, B., Herrmann, M. J., Junghöfer, M., Klahn, A. L., Schwarzmeier, H., Seeger, F., Siminski, N., Straube, T., Dannlowski, U., Lueken, U., Leehr, E. J. & Hilbert, K. (2023). Individual-Level Prediction of exposure therapy outcome using structural and functional MRI data in Spider Phobia: a Machine-Learning Study. Depression and Anxiety, 2023, 1–11. https://doi.org/10.1155/2023/8594273
Roesmann, K., Leehr, E. J., Böhnlein, J., Gathmann, B., Herrmann, M. J., Junghöfer, M., Schwarzmeier, H., … & Lueken, U. (2023). Mechanisms of action underlying virtual reality exposure treatment in spider phobia: pivotal role of within-session fear reduction. Journal of Anxiety Disorders, 102790. 10.1016/j.janxdis.2023.102790
Groenewold, N. A., Bas-Hoogendam, J.-M., Amod, A. R., Laansma, M. A., Van Velzen, L. S., Aghajani, M., Hilbert, K., … Lueken, U., … & Van der Wee, N. J. A. (2023). Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group. Molecular Psychiatry, 28, 1079-1089. 10.1038/s41380-022-01933-9
Rane, R. P., Musial, M. P. M., Beck, A. M., Rapp, M. A., Schlagenhauf, F., Banaschewski, T., Bokde, A. L., Martinot, M. P., Artiges, É., Nees, F., Lemaître, H., Hohmann, S., Schümann, G., Walter, H., Heinz, A. & Ritter, K. (2023). Uncontrolled eating and sensation-seeking partially explain the prediction of future binge drinking from adolescent brain structure. NeuroImage: Clinical, 40, 103520. https://doi.org/10.1016/j.nicl.2023.103520
Rane, R. P., De Man, E. F., Kim, J., Görgen, K., Tschorn, M., Rapp, M. A., Banaschewski, T., Bokde, A. L., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Brühl, R., Martinot, J., Martinot, M. P., Artiges, É., Nees, F., Papadopoulos, D., . . . Ritter, K. (2022). Structural differences in adolescent brains can predict alcohol misuse. eLife, 11. https://doi.org/10.7554/elife.77545